About Receptor-transporting protein 1
Receptor-transporting protein 1 (RTP1) is a protein
from Homo sapiens identified by UniProt accession
P59025, 263 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Receptor-transporting protein 1 |
|---|
| UniProt accession | P59025 |
|---|
| Gene | RTP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 263 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (32)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- ovarian cancer · score 0.18
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- blood protein measurement · score 0.09
- Female infertility due to fertilization defect · score 0.06
- Rare genetic female infertility · score 0.06
- female infertility due to oocyte meiotic arrest · score 0.05
- protein measurement · score 0.05
- Male infertility with spermatogenesis disorder due to single gene mutation · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P59025-F1 | alphafold | PREDICTED | 75.46 | — |
Amino-acid sequence (263 residues)
MRIFRPWRLR CPALHLPSLS VFSLRWKLPS LTTDETMCKS VTTDEWKKVF YEKMEEAKPA DSWDLIIDPN LKHNVLSPGW KQYLELHASG RFHCSWCWHT WQSPYVVILF HMFLDRAQRA GSVRMRVFKQ LCYECGTARL DESSMLEENI EGLVDNLITS LREQCYGERG GQYRIHVASR QDNRRHRGEF CEACQEGIVH WKPSEKLLEE EATTYTFSRA PSPTKSQDQT GSGWNFCSIP WCLFWATVLL LIIYLQFSFR SSV
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