D-amino acid oxidase regulator (DAOA)

About D-amino acid oxidase regulator

D-amino acid oxidase regulator (DAOA) is a protein from Homo sapiens identified by UniProt accession P59103, 153 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	D-amino acid oxidase regulator
UniProt accession	P59103
Gene	DAOA
Organism	Homo sapiens
Length	153 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

schizophrenia · score 0.41
Varicose veins · score 0.30
protein measurement · score 0.27
visual perception measurement · score 0.27
pathological myopia · score 0.27
intelligence · score 0.22
cognitive function measurement · score 0.21
mathematical ability · score 0.20
self reported educational attainment · score 0.20
blood protein measurement · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P59103-F1	alphafold	PREDICTED	46.88	—

Amino-acid sequence (153 residues)

MLEKLMGADS LQLFRSRYTL GKIYFIGFQR SILLSKSENS LNSIAKETEE GRETVTRKEG WKRRHEDGYL EMAQRHLQRS LCPWVSYLPQ PYAELEEVSS HVGKVFMARN YEFLAYEASK DRRQPLERMW TCNYNQQKDQ SCNHKEITST KAE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards