About Taste receptor type 2 member 41
Taste receptor type 2 member 41 (TAS2R41) is a protein
from Homo sapiens identified by UniProt accession
P59536, 307 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Taste receptor type 2 member 41 |
|---|
| UniProt accession | P59536 |
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| Gene | TAS2R41 |
|---|
| Organism | Homo sapiens |
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| Length | 307 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (8)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.22
- lung adenocarcinoma · score 0.18
- protein measurement · score 0.18
- breast adenocarcinoma · score 0.16
- squamous cell lung carcinoma · score 0.13
- head and neck squamous cell carcinoma · score 0.13
- Alzheimer disease · score 0.04
- nicotine dependence · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P59536-F1 | alphafold | PREDICTED | 85.23 | — |
Amino-acid sequence (307 residues)
MQAALTAFFV LLFSLLSLLG IAANGFIVLV LGREWLRYGR LLPLDMILIS LGASRFCLQL VGTVHNFYYS AQKVEYSGGL GRQFFHLHWH FLNSATFWFC SWLSVLFCVK IANITHSTFL WLKWRFPGWV PWLLLGSVLI SFIITLLFFW VNYPVYQEFL IRKFSGNMTY KWNTRIETYY FPSLKLVIWS IPFSVFLVSI MLLINSLRRH TQRMQHNGHS LQDPSTQAHT RALKSLISFL ILYALSFLSL IIDAAKFISM QNDFYWPWQI AVYLCISVHP FILIFSNLKL RSVFSQLLLL ARGFWVA
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