About Taste receptor type 2 member 31
Taste receptor type 2 member 31 (TAS2R31) is a protein
from Homo sapiens identified by UniProt accession
P59538, 309 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Taste receptor type 2 member 31 |
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| UniProt accession | P59538 |
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| Gene | TAS2R31 |
|---|
| Organism | Homo sapiens |
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| Length | 309 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (16)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.16
- head and neck squamous cell carcinoma · score 0.13
- sensory perception of bitter taste · score 0.08
- blood protein measurement · score 0.07
- coffee consumption · score 0.06
- actinic keratosis · score 0.05
- squamous cell carcinoma · score 0.04
- tea consumption measurement · score 0.04
- coffee consumption measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P59538-F1 | alphafold | PREDICTED | 87.61 | — |
Amino-acid sequence (309 residues)
MTTFIPIIFS SVVVVLFVIG NFANGFIALV NSIERVKRQK ISFADQILTA LAVSRVGLLW VLLLNWYSTV FNPAFYSVEV RTTAYNVWAV TGHFSNWLAT SLSIFYLLKI ANFSNLIFLH LKRRVKSVIL VMLLGPLLFL ACQLFVINMK EIVRTKEYEG NLTWKIKLRS AVYLSDATVT TLGNLVPFTL TLLCFLLLIC SLCKHLKKMQ LHGKGSQDPS TKVHIKALQT VIFFLLLCAV YFLSIMISVW SFGSLENKPV FMFCKAIRFS YPSIHPFILI WGNKKLKQTF LSVLRQVRYW VKGEKPSSP
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