Taste receptor type 2 member 30 (TAS2R30)

About Taste receptor type 2 member 30

Taste receptor type 2 member 30 (TAS2R30) is a protein from Homo sapiens identified by UniProt accession P59541, 319 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Taste receptor type 2 member 30
UniProt accession	P59541
Gene	TAS2R30
Organism	Homo sapiens
Length	319 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (12)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.22
lung adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.16
sensory perception of bitter taste · score 0.15
head and neck squamous cell carcinoma · score 0.13
blood protein measurement · score 0.11
gastric adenocarcinoma · score 0.10
actinic keratosis · score 0.06
sebaceous of Jadassohn nevus · score 0.06
squamous cell carcinoma · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P59541-F1	alphafold	PREDICTED	85.35	—

Amino-acid sequence (319 residues)

MITFLPIIFS ILIVVIFVIG NFANGFIALV NSIEWVKRQK ISFVDQILTA LAVSRVGLLW VLLLHWYATQ LNPAFYSVEV RITAYNVWAV TNHFSSWLAT SLSMFYLLRI ANFSNLIFLR IKRRVKSVVL VILLGPLLFL VCHLFVINMD ETVWTKEYEG NVTWKIKLRS AMYHSNMTLT MLANFVPLTL TLISFLLLIC SLCKHLKKMQ LHGKGSQDPS TKVHIKALQT VTSFLLLCAI YFLSMIISVC NFGRLEKQPV FMFCQAIIFS YPSTHPFILI LGNKKLKQIF LSVLRHVRYW VKDRSLRLHR FTRGALCVF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards