Taste receptor type 2 member 20 (TAS2R20)

About Taste receptor type 2 member 20

Taste receptor type 2 member 20 (TAS2R20) is a protein from Homo sapiens identified by UniProt accession P59543, 309 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Taste receptor type 2 member 20
UniProt accession	P59543
Gene	TAS2R20
Organism	Homo sapiens
Length	309 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (4)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (16)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.22
lung adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.16
squamous cell lung carcinoma · score 0.13
head and neck squamous cell carcinoma · score 0.13
sensory perception of bitter taste · score 0.12
Familial prostate cancer · score 0.11
prostate carcinoma · score 0.11
prostate cancer · score 0.11
blood protein measurement · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P59543-F1	alphafold	PREDICTED	87.15	—

Amino-acid sequence (309 residues)

MMSFLHIVFS ILVVVAFILG NFANGFIALI NFIAWVKRQK ISSADQIIAA LAVSRVGLLW VILLHWYSTV LNPTSSNLKV IIFISNAWAV TNHFSIWLAT SLSIFYLLKI VNFSRLIFHH LKRKAKSVVL VIVLGSLFFL VCHLVMKHTY INVWTEECEG NVTWKIKLRN AMHLSNLTVA MLANLIPFTL TLISFLLLIY SLCKHLKKMQ LHGKGSQDPS TKIHIKALQT VTSFLILLAI YFLCLIISFW NFKMRPKEIV LMLCQAFGII YPSFHSFILI WGNKTLKQTF LSVLWQVTCW AKGQNQSTP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards