Taste receptor type 2 member 60 (TAS2R60)

About Taste receptor type 2 member 60

Taste receptor type 2 member 60 (TAS2R60) is a protein from Homo sapiens identified by UniProt accession P59551, 318 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Taste receptor type 2 member 60
UniProt accession	P59551
Gene	TAS2R60
Organism	Homo sapiens
Length	318 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (11)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.22
lung adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.16
squamous cell lung carcinoma · score 0.13
head and neck squamous cell carcinoma · score 0.13
gastric adenocarcinoma · score 0.10
Alzheimer disease · score 0.09
sex hormone-binding globulin measurement · score 0.09
serum gamma-glutamyl transferase measurement · score 0.09
calcium measurement · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P59551-F1	alphafold	PREDICTED	77.87	—

Amino-acid sequence (318 residues)

MNGDHMVLGS SVTDKKAIIL VTILLLLRLV AIAGNGFITA ALGVEWVLRR MLLPCDKLLV SLGASRFCLQ SVVMGKTIYV FLHPMAFPYN PVLQFLAFQW DFLNAATLWS STWLSVFYCV KIATFTHPVF FWLKHKLSGW LPWMLFSSVG LSSFTTILFF IGNHRMYQNY LRNHLQPWNV TGDSIRSYCE KFYLFPLKMI TWTMPTAVFF ICMILLITSL GRHRKKALLT TSGFREPSVQ AHIKALLALL SFAMLFISYF LSLVFSAAGI FPPLDFKFWV WESVIYLCAA VHPIILLFSN CRLRAVLKSR RSSRCGTP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards