Glutathione peroxidase 6 (GPX6)

Homo sapiens — UniProt P59796

Gene: GPX6Homo sapiensSwissProt reviewed

About Glutathione peroxidase 6

Glutathione peroxidase 6 (GPX6) is a protein from Homo sapiens identified by UniProt accession P59796, 221 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein nameGlutathione peroxidase 6
UniProt accessionP59796
GeneGPX6
OrganismHomo sapiens
Length221 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (47)

Diseases linked to this target (Open Targets).

  • body height · score 0.31
  • sitting height measurement · score 0.28
  • ulcerative colitis · score 0.28
  • calcium measurement · score 0.27
  • malignant epithelial tumor of ovary · score 0.25
  • peak expiratory flow · score 0.13
  • sex hormone-binding globulin measurement · score 0.10
  • forced expiratory volume · score 0.09
  • attention deficit hyperactivity disorder · score 0.09
  • mean corpuscular volume · score 0.08

3D Structure

Predicted structure for P59796 is available from the AlphaFold Protein Structure Database.

Amino-acid sequence (221 residues)

MFQQFQASCL VLFFLVGFAQ QTLKPQNRKV DCNKGVTGTI YEYGALTLNG EEYIQFKQFA GKHVLFVNVA AYUGLAAQYP ELNALQEELK NFGVIVLAFP CNQFGKQEPG TNSEILLGLK YVCPGSGFVP SFQLFEKGDV NGEKEQKVFT FLKNSCPPTS DLLGSSSQLF WEPMKVHDIR WNFEKFLVGP DGVPVMHWFH QAPVSTVKSD ILEYLKQFNT H

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Quick facts

UniProtP59796
GeneGPX6
OrganismHomo sapiens
Length221
Binders0
Diseases47
View on UniProt