BPI fold-containing family B member 3 (BPIFB3)

About BPI fold-containing family B member 3

BPI fold-containing family B member 3 (BPIFB3) is a protein from Homo sapiens identified by UniProt accession P59826, 472 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	BPI fold-containing family B member 3
UniProt accession	P59826
Gene	BPIFB3
Organism	Homo sapiens
Length	472 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

breast carcinoma · score 0.02
bacterial disease · score 0.01
Zika virus infectious disease · score 0.00
Flavivirus Infections · score 0.00
nail-patella syndrome · score 0.00
Salmonella Infections · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P59826-F1	alphafold	PREDICTED	81.26	—

Amino-acid sequence (472 residues)

MLALWSLLLL WGLATPCQEL LETVGTLARI DKDELGKAIQ NSLVGEPILQ NVLGSVTAVN RGLLGSGGLL GGGGLLGHGG VFGVVEELSG LKIEELTLPK VLLKLLPGFG VQLSLHTKVG MHCSGPLGGL LQLAAEVNVT SRVALAVSSR GTPILILKRC STLLGHISLF SGLLPTPLFG VVEQMLFKVL PGLLCPVVDS VLGVVNELLG AVLGLVSLGA LGSVEFSLAT LPLISNQYIE LDINPIVKSV AGDIIDFPKS RAPAKVPPKK DHTSQVMVPL YLFNTTFGLL QTNGALDMDI TPELVPSDVP LTTTDLAALL PEALGKLPLH QQLLLFLRVR EAPTVTLHNK KALVSLPANI HVLFYVPKGT PESLFELNSV MTVRAQLAPS ATKLHISLSL ERLSVKVASS FTHAFDGSRL EEWLSHVVGA VYAPKLNVAL DVGIPLPKVL NINFSNSVLE IVENAVVLTV AS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards