About Leukocyte immunoglobulin-like receptor subfamily A member 4
Leukocyte immunoglobulin-like receptor subfamily A member 4 (LILRA4) is a protein
from Homo sapiens identified by UniProt accession
P59901, 499 residues long.
MolForge cross-references it against 0 known binders and
115 disease associations.
Target properties
| Protein name | Leukocyte immunoglobulin-like receptor subfamily A member 4 |
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| UniProt accession | P59901 |
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| Gene | LILRA4 |
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| Organism | Homo sapiens |
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| Length | 499 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (115)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.34
- visual perception measurement · score 0.29
- alopecia areata · score 0.07
- systemic lupus erythematosus · score 0.07
- acquired idiopathic inflammatory myopathy · score 0.07
- lupus nephritis · score 0.07
- discoid lupus erythematosus · score 0.07
- common variable immunodeficiency · score 0.06
- Chronic mucocutaneous candidosis · score 0.06
- isolated agammaglobulinemia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P59901-F1 | alphafold | PREDICTED | 83.05 | — |
Amino-acid sequence (499 residues)
MTLILTSLLF FGLSLGPRTR VQAENLLKPI LWAEPGPVIT WHNPVTIWCQ GTLEAQGYRL DKEGNSMSRH ILKTLESENK VKLSIPSMMW EHAGRYHCYY QSPAGWSEPS DPLELVVTAY SRPTLSALPS PVVTSGVNVT LRCASRLGLG RFTLIEEGDH RLSWTLNSHQ HNHGKFQALF PMGPLTFSNR GTFRCYGYEN NTPYVWSEPS DPLQLLVSGV SRKPSLLTLQ GPVVTPGENL TLQCGSDVGY IRYTLYKEGA DGLPQRPGRQ PQAGLSQANF TLSPVSRSYG GQYRCYGAHN VSSEWSAPSD PLDILIAGQI SDRPSLSVQP GPTVTSGEKV TLLCQSWDPM FTFLLTKEGA AHPPLRLRSM YGAHKYQAEF PMSPVTSAHA GTYRCYGSRS SNPYLLSHPS EPLELVVSGA TETLNPAQKK SDSKTAPHLQ DYTVENLIRM GVAGLVLLFL GILLFEAQHS QRSPPRCSQE ANSRKDNAPF RVVEPWEQI
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