DnaJ homolog subfamily B member 13 (DNAJB13)

About DnaJ homolog subfamily B member 13

DnaJ homolog subfamily B member 13 (DNAJB13) is a protein from Homo sapiens identified by UniProt accession P59910, 316 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	DnaJ homolog subfamily B member 13
UniProt accession	P59910
Gene	DNAJB13
Organism	Homo sapiens
Length	316 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

primary ciliary dyskinesia · score 0.58
neurodegenerative disease · score 0.36
mean corpuscular volume · score 0.15
Cough · score 0.12
mean corpuscular hemoglobin concentration · score 0.10
brain measurement · score 0.06
mean platelet volume · score 0.03
insomnia measurement · score 0.02
blood protein measurement · score 0.02
cryptorchidism · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P59910-F1	alphafold	PREDICTED	86.23	—

Amino-acid sequence (316 residues)

MGQDYYSVLG ITRNSEDAQI KQAYRRLALK HHPLKSNEPS SAEIFRQIAE AYDVLSDPMK RGIYDKFGEE GLKGGIPLEF GSQTPWTTGY VFHGKPEKVF HEFFGGNNPF SEFFDAEGSE VDLNFGGLQG RGVKKQDPQV ERDLYLSLED LFFGCTKKIK ISRRVLNEDG YSSTIKDKIL TIDVKPGWRQ GTRITFEKEG DQGPNIIPAD IIFIVKEKLH PRFRRENDNL FFVNPIPLGK ALTCCTVEVR TLDDRLLNIP INDIIHPKYF KKVPGEGMPL PEDPTKKGDL FIFFDIQFPT RLTPQKKQML RQALLT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards