Mitochondrial coiled-coil domain protein 1 (MCCD1)

About Mitochondrial coiled-coil domain protein 1

Mitochondrial coiled-coil domain protein 1 (MCCD1) is a protein from Homo sapiens identified by UniProt accession P59942, 119 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Mitochondrial coiled-coil domain protein 1
UniProt accession	P59942
Gene	MCCD1
Organism	Homo sapiens
Length	119 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

hypothyroidism · score 0.21
pulse pressure measurement · score 0.13
cervical carcinoma · score 0.11
waist-hip ratio · score 0.11
blood protein measurement · score 0.09
lymphocyte count · score 0.06
allergic disease · score 0.06
cerebrospinal fluid biomarker measurement · score 0.05
17-hydroxyprogesterone measurement · score 0.05
insomnia measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P59942-F1	alphafold	PREDICTED	65.44	—

Amino-acid sequence (119 residues)

MVLPLPWLSR YHFLRLLLPS WSLAPQGSHG CCSQNPKASM EEQTSSRGNG KMTSPPRGPG THRTAELARA EELLEQQLEL YQALLEGQEG AWEAQALVLK IQKLKEQMRR HQESLGGGA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards