Keratin-associated protein 12-1 (KRTAP12-1)

About Keratin-associated protein 12-1

Keratin-associated protein 12-1 (KRTAP12-1) is a protein from Homo sapiens identified by UniProt accession P59990, 96 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	Keratin-associated protein 12-1
UniProt accession	P59990
Gene	KRTAP12-1
Organism	Homo sapiens
Length	96 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (2)

Diseases linked to this target (Open Targets).

prostate adenocarcinoma · score 0.18
small cell lung carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P59990-F1	alphafold	PREDICTED	44.54	—

Amino-acid sequence (96 residues)

MCHTSCSSGC QPACCAPSPC QASCYIPVGC QSSVCVPVSF KPAVCVPVRC QSSVCVPVSC RPVVYAAPSC QSSGCCQPSC TSVLCRPISC STPSCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards