Keratin-associated protein 12-2 (KRTAP12-2)

About Keratin-associated protein 12-2

Keratin-associated protein 12-2 (KRTAP12-2) is a protein from Homo sapiens identified by UniProt accession P59991, 146 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	Keratin-associated protein 12-2
UniProt accession	P59991
Gene	KRTAP12-2
Organism	Homo sapiens
Length	146 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
small cell lung carcinoma · score 0.01
diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P59991-F1	alphafold	PREDICTED	71.03	—

Amino-acid sequence (146 residues)

MCHTSCSSGC QPACCAPSPC QPACCVPSSC QASCCVPVGC QSSVCVPVSF KPAVCLPVSC QSSVCVPMSF KSAVCVPVSC QSSVCVPVSC RPIVCAAPSC QSSLCVPVSC RPVVYAAPSC QSSGCCQPSC TSVLCRPISY SISSCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards