Transcription elongation factor 1 homolog (ELOF1)

About Transcription elongation factor 1 homolog

Transcription elongation factor 1 homolog (ELOF1) is a protein from Homo sapiens identified by UniProt accession P60002, 83 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Transcription elongation factor 1 homolog
UniProt accession	P60002
Gene	ELOF1
Organism	Homo sapiens
Length	83 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.50
blood protein measurement · score 0.06
dilated cardiomyopathy 1I · score 0.03
nephrogenic syndrome of inappropriate antidiuresis · score 0.03
obesity-colitis-hypothyroidism-cardiac hypertrophy-developmental delay syndrome · score 0.03
neoplasm · score 0.01
Ascites · score 0.01
colorectal adenoma · score 0.01
infection · score 0.00
infect · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60002-F1	alphafold	PREDICTED	86.12	—

Amino-acid sequence (83 residues)

MGRRKSKRKP PPKKKMTGTL ETQFTCPFCN HEKSCDVKMD RARNTGVISC TVCLEEFQTP ITYLSEPVDV YSDWIDACEA ANQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards