About Keratin-associated protein 10-10
Keratin-associated protein 10-10 (KRTAP10-10) is a protein
from Homo sapiens identified by UniProt accession
P60014, 251 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Keratin-associated protein 10-10 |
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| UniProt accession | P60014 |
|---|
| Gene | KRTAP10-10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 251 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.39
- head and neck squamous cell carcinoma · score 0.18
- glioblastoma multiforme · score 0.18
- breast adenocarcinoma · score 0.18
- thyroid gland adenocarcinoma · score 0.16
- esophageal cancer · score 0.14
- small cell lung carcinoma · score 0.01
- diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P60014-F1 | alphafold | PREDICTED | 38.00 | — |
Amino-acid sequence (251 residues)
MAASTMSICS SACTDSWRVV DCPESCCEPC CCAPAPSLTL VCTPVSCVSS PCCQTACEPS ACQSGYTSSC TTPCYQQSSC QPDCCTSSPC QQACCVPVCC VPVCCVPVCN KPVCFVPTCS ESSPSCCQQS SCQPTCCTSS PCQQACCVPV CSKSVCYVPV CSGASTSCCQ QSSCQPACCT ASCCRPSSSV SLLCHPVCKS TCCVPVPSCG ASASSCQPSC CRTASCVSLL CRPVCSRPAC YSLCSGQKSS C
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