Protein transport protein Sec61 subunit gamma (SEC61G)

About Protein transport protein Sec61 subunit gamma

Protein transport protein Sec61 subunit gamma (SEC61G) is a protein from Homo sapiens identified by UniProt accession P60059, 68 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.

Target properties

Protein name	Protein transport protein Sec61 subunit gamma
UniProt accession	P60059
Gene	SEC61G
Organism	Homo sapiens
Length	68 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (67)

Diseases linked to this target (Open Targets).

self reported educational attainment · score 0.38
mathematical ability · score 0.33
glioblastoma multiforme · score 0.30
neuroimaging measurement · score 0.30
glioma · score 0.30
brain measurement · score 0.30
cholesteryl ester 20:4 measurement · score 0.28
central nervous system cancer · score 0.28
brain volume measurement · score 0.27
thalamus volume · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60059-F1	alphafold	PREDICTED	91.91	—

Amino-acid sequence (68 residues)

MDQVMQFVEP SRQFVKDSIR LVKRCTKPDR KEFQKIAMAT AIGFAIMGFI GFFVKLIHIP INNIIVGG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards