Nanos homolog 3 (NANOS3)

About Nanos homolog 3

Nanos homolog 3 (NANOS3) is a protein from Homo sapiens identified by UniProt accession P60323, 173 residues long. MolForge cross-references it against 0 known binders and 195 disease associations.

Target properties

Protein name	Nanos homolog 3
UniProt accession	P60323
Gene	NANOS3
Organism	Homo sapiens
Length	173 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (195)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.36
primary ovarian insufficiency · score 0.20
mathematical ability · score 0.15
monocyte count · score 0.13
breast carcinoma · score 0.12
peak expiratory flow · score 0.10
lymphocyte count · score 0.10
myeloid white cell count · score 0.09
azoospermia · score 0.09
leukocyte count · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60323-F1	alphafold	PREDICTED	70.94	—

Amino-acid sequence (173 residues)

MGTFDLWTDY LGLAHLVRAL SGKEGPETRL SPQPEPEPML EPDQKRSLES SPAPERLCSF CKHNGESRAI YQSHVLKDEA GRVLCPILRD YVCPQCGATR ERAHTRRFCP LTGQGYTSVY SHTTRNSAGK KLVRPDKAKT QDTGHRRGGG GGAGFRGAGK SEPSPSCSPS MST

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards