Keratin-associated protein 12-3 (KRTAP12-3)

About Keratin-associated protein 12-3

Keratin-associated protein 12-3 (KRTAP12-3) is a protein from Homo sapiens identified by UniProt accession P60328, 96 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Keratin-associated protein 12-3
UniProt accession	P60328
Gene	KRTAP12-3
Organism	Homo sapiens
Length	96 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
clear cell renal carcinoma · score 0.18
glioblastoma multiforme · score 0.18
small cell lung carcinoma · score 0.00
diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60328-F1	alphafold	PREDICTED	42.43	—

Amino-acid sequence (96 residues)

MCHTSCSPAC QPTCCIHSPC QASCYVPVSC QSSVCMPVSC TRIVCVAPSC QPSVCVPVSC RPIIYVTPSC QSSGCCQPPC TTALCRPISC STPSCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards