Keratin-associated protein 12-4 (KRTAP12-4)

About Keratin-associated protein 12-4

Keratin-associated protein 12-4 (KRTAP12-4) is a protein from Homo sapiens identified by UniProt accession P60329, 112 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Keratin-associated protein 12-4
UniProt accession	P60329
Gene	KRTAP12-4
Organism	Homo sapiens
Length	112 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.18
ovarian cancer · score 0.18
esophageal cancer · score 0.14
diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60329-F1	alphafold	PREDICTED	43.66	—

Amino-acid sequence (112 residues)

MCHTSHSSGC PMACPGSPCC VPSTCYPPEG YGTSCCCSAP CVALLCRPLC GVSTCCQPAC CVPSPCQVAC CVPVSCKPVL CVASFCPTSG CCQPFCPTLV YRPVTWSTPT GC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards