Keratin-associated protein 10-2 (KRTAP10-2)

About Keratin-associated protein 10-2

Keratin-associated protein 10-2 (KRTAP10-2) is a protein from Homo sapiens identified by UniProt accession P60368, 255 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Keratin-associated protein 10-2
UniProt accession	P60368
Gene	KRTAP10-2
Organism	Homo sapiens
Length	255 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.28
glioblastoma multiforme · score 0.18
head and neck squamous cell carcinoma · score 0.18
breast adenocarcinoma · score 0.18
low grade glioma · score 0.11
metabolite measurement · score 0.09
hair shape measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60368-F1	alphafold	PREDICTED	36.23	—

Amino-acid sequence (255 residues)

MAASTMSICS SACTNSWQVD DCPESCCELP CGTPSCCAPA PCLTLVCTPV SCVSSPCCQA ACEPSACQSG CTSSCTPSCC QQSSCQPACC TSSPCQQACC VPVCCKPVCC VPVCCGASSC CQQSSCQPAC CASSSCQQSC RVPVCCKAVC CVPTCSESSS SCCQQSSCQP ACCTSSPCQQ SCCVSVCCKP VCCKSICCVP VCSGASSPCC QQSSCQPACC TSSCCRPSSS VSLLCRPVCS RPASCSFSSG QKSSC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards