About Keratin-associated protein 10-3
Keratin-associated protein 10-3 (KRTAP10-3) is a protein
from Homo sapiens identified by UniProt accession
P60369, 221 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Keratin-associated protein 10-3 |
|---|
| UniProt accession | P60369 |
|---|
| Gene | KRTAP10-3 |
|---|
| Organism | Homo sapiens |
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| Length | 221 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- clear cell renal carcinoma · score 0.18
- glioblastoma multiforme · score 0.18
- thyroid gland adenocarcinoma · score 0.16
- breast ductal adenocarcinoma · score 0.11
- metabolite measurement · score 0.07
- autosomal recessive hypohidrotic ectodermal dysplasia · score 0.01
- hearing loss, autosomal recessive · score 0.01
- deafness · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P60369-F1 | alphafold | PREDICTED | 39.02 | — |
Amino-acid sequence (221 residues)
MATSTMSVCS SAYSDSWQVD ACPESCCEPP CCATSCCAPA PCLTLVCTPV SCVSSPCCQA ACEPSPCQSG CTSSCTPSCC QQSSCQPACC TSSPCQQACC VPVCCKPVCC VPVCCKPVCC KPICCVPVCS GASSSCCQQS SRQPACCTTS CCRPSSSVSL LCRPVCRSTC CVPIPSCCAP ASTCQPSCCR PASCVSLLCR PTCSRLSSAC CGLSSGQKSS C
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