Keratin-associated protein 10-5 (KRTAP10-5)

About Keratin-associated protein 10-5

Keratin-associated protein 10-5 (KRTAP10-5) is a protein from Homo sapiens identified by UniProt accession P60370, 271 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Keratin-associated protein 10-5
UniProt accession	P60370
Gene	KRTAP10-5
Organism	Homo sapiens
Length	271 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
clear cell renal carcinoma · score 0.18
breast adenocarcinoma · score 0.18
thyroid gland adenocarcinoma · score 0.16
diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60370-F1	alphafold	PREDICTED	35.71	—

Amino-acid sequence (271 residues)

MAACTMSVCS SACSDSWRVD DCPESCCEPP CGTAPCLTLV CTPVSCVSSP CCQAACEPSP CQSGCTSSCT PSCCQPACCA SSPCQQACCV PVCCKPVCCL PTCSKDSSSC CQQSSCQPTC CASSSCQQSC CVPVCCKPVC CVPTCSEDSS SCCQHSSCQP TCCTSSPCQQ SCYVPVCCKP VCCKPICCVP VCSGASTSCC QQSSCQPACC TTSCCRPSSS VSLLCRPICR PACCLPISSC CAPASSYQAS CCRPASCVSL LCRPACSPLA C

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards