Keratin-associated protein 10-8 (KRTAP10-8)

About Keratin-associated protein 10-8

Keratin-associated protein 10-8 (KRTAP10-8) is a protein from Homo sapiens identified by UniProt accession P60410, 259 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Keratin-associated protein 10-8
UniProt accession	P60410
Gene	KRTAP10-8
Organism	Homo sapiens
Length	259 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.25
head and neck squamous cell carcinoma · score 0.18
breast adenocarcinoma · score 0.18
esophageal cancer · score 0.14
diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60410-F1	alphafold	PREDICTED	36.38	—

Amino-acid sequence (259 residues)

MADACCTRTY VIAASTMSVC SSDVGHVSRV SSPSTCTGSS WQVDNCQESC CEPRSCASSC CTPSCCAPAP CLALVCAPVS CEPSPCQSGC TDSCTPSCCQ QSSCQPACCT SSPCQQACCV PVCCKSNCCK PVCCVSICSG ASSPCCQQSS CQSACCTFSP CQQACCVPIC CKPICCVPVC SGASSLCCQK SSCQPACCTT SCCRPSSSVS LLCRPVCRPA CCVPVPSCCV PASSCQPSCC HPASCLSFLC RPACSRLAC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards