Protein transport protein Sec61 subunit beta (SEC61B)

About Protein transport protein Sec61 subunit beta

Protein transport protein Sec61 subunit beta (SEC61B) is a protein from Homo sapiens identified by UniProt accession P60468, 96 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.

Target properties

Protein name	Protein transport protein Sec61 subunit beta
UniProt accession	P60468
Gene	SEC61B
Organism	Homo sapiens
Length	96 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (67)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
mathematical ability · score 0.23
asthma · score 0.22
vital capacity · score 0.19
polycystic liver disease 1 · score 0.18
smoking status measurement · score 0.18
cognitive function measurement · score 0.18
urate measurement · score 0.16
body mass index · score 0.15
body height · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60468-F1	alphafold	PREDICTED	57.46	—

Amino-acid sequence (96 residues)

MPGPTPSGTN VGSSGRSPSK AVAARAAGST VRQRKNASCG TRSAGRTTSA GTGGMWRFYT EDSPGLKVGP VPVLVMSLLF IASVFMLHIW GKYTRS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards