About Serine/threonine-protein phosphatase 4 catalytic subunit
Serine/threonine-protein phosphatase 4 catalytic subunit (PPP4C) is a protein
from Homo sapiens identified by UniProt accession
P60510, 307 residues long.
MolForge cross-references it against 0 known binders and
122 disease associations.
Target properties
| Protein name | Serine/threonine-protein phosphatase 4 catalytic subunit |
|---|
| UniProt accession | P60510 |
|---|
| Gene | PPP4C |
|---|
| Organism | Homo sapiens |
|---|
| Length | 307 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (122)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.43
- breast adenocarcinoma · score 0.25
- clear cell renal carcinoma · score 0.10
- neoplasm · score 0.09
- eosinophil count · score 0.09
- lung adenocarcinoma · score 0.08
- diffuse large B-cell lymphoma · score 0.07
- colorectal carcinoma · score 0.07
- Insulin resistance · score 0.07
- eosinophil percentage of leukocytes · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P60510-F1 | alphafold | PREDICTED | 94.80 | — |
Amino-acid sequence (307 residues)
MAEISDLDRQ IEQLRRCELI KESEVKALCA KAREILVEES NVQRVDSPVT VCGDIHGQFY DLKELFRVGG DVPETNYLFM GDFVDRGFYS VETFLLLLAL KVRYPDRITL IRGNHESRQI TQVYGFYDEC LRKYGSVTVW RYCTEIFDYL SLSAIIDGKI FCVHGGLSPS IQTLDQIRTI DRKQEVPHDG PMCDLLWSDP EDTTGWGVSP RGAGYLFGSD VVAQFNAAND IDMICRAHQL VMEGYKWHFN ETVLTVWSAP NYCYRCGNVA AILELDEHLQ KDFIIFEAAP QETRGIPSKK PVADYFL
Explore Serine/threonine-protein phosphatase 4 catalytic subunit with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets