Interleukin-2 (IL2)

About Interleukin-2

Interleukin-2 (IL2) is a protein from Homo sapiens identified by UniProt accession P60568, 153 residues long. MolForge cross-references it against 0 known binders and 1,987 disease associations.

Target properties

Protein name	Interleukin-2
UniProt accession	P60568
Gene	IL2
Organism	Homo sapiens
Length	153 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (2)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (1987)

Diseases linked to this target (Open Targets).

breast neoplasm · score 0.42
eosinophil count · score 0.31
seasonal allergic rhinitis · score 0.30
breast adenocarcinoma · score 0.29
psoriasis · score 0.29
allergic disease · score 0.28
allergic rhinitis · score 0.26
endometrial cancer · score 0.25
asthma · score 0.23
type 1 diabetes mellitus · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60568-F1	alphafold	PREDICTED	84.11	—

Amino-acid sequence (153 residues)

MYRMQLLSCI ALSLALVTNS APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR WITFCQSIIS TLT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards