Reactive oxygen species modulator 1 (ROMO1)

About Reactive oxygen species modulator 1

Reactive oxygen species modulator 1 (ROMO1) is a protein from Homo sapiens identified by UniProt accession P60602, 79 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.

Target properties

Protein name	Reactive oxygen species modulator 1
UniProt accession	P60602
Gene	ROMO1
Organism	Homo sapiens
Length	79 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (79)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.48
glioblastoma · score 0.07
cancer · score 0.07
neoplasm · score 0.07
urinary bladder carcinoma · score 0.06
non-small cell lung carcinoma · score 0.06
attention deficit hyperactivity disorder · score 0.06
type 2 diabetes mellitus · score 0.05
Tourette syndrome · score 0.05
schizophrenia 15 · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60602-F1	alphafold	PREDICTED	78.67	—

Amino-acid sequence (79 residues)

MPVAVGPYGQ SQPSCFDRVK MGFVMGCAVG MAAGALFGTF SCLRIGMRGR ELMGGIGKTM MQSGGTFGTF MAIGMGIRC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards