About Ubiquitin-conjugating enzyme E2 G2
Ubiquitin-conjugating enzyme E2 G2 (UBE2G2) is a protein
from Homo sapiens identified by UniProt accession
P60604, 165 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Ubiquitin-conjugating enzyme E2 G2 |
|---|
| UniProt accession | P60604 |
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| Gene | UBE2G2 |
|---|
| Organism | Homo sapiens |
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| Length | 165 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (29)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- lysosomal storage disease · score 0.32
- serum alanine aminotransferase measurement · score 0.17
- esophageal squamous cell carcinoma · score 0.15
- balding measurement · score 0.08
- type 2 diabetes mellitus · score 0.05
- hair shape measurement · score 0.03
- alopecia · score 0.03
- Hypoglycemia · score 0.02
- neurofibrillary tangles measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P60604-F1 | alphafold | PREDICTED | 94.42 | — |
Amino-acid sequence (165 residues)
MAGTALKRLM AEYKQLTLNP PEGIVAGPMN EENFFEWEAL IMGPEDTCFE FGVFPAILSF PLDYPLSPPK MRFTCEMFHP NIYPDGRVCI SILHAPGDDP MGYESSAERW SPVQSVEKIL LSVVSMLAEP NDESGANVDA SKMWRDDREQ FYKIAKQIVQ KSLGL
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