Cortexin-1 (CTXN1)

About Cortexin-1

Cortexin-1 (CTXN1) is a protein from Homo sapiens identified by UniProt accession P60606, 82 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Cortexin-1
UniProt accession	P60606
Gene	CTXN1
Organism	Homo sapiens
Length	82 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.18
sebaceous of Jadassohn nevus · score 0.05
actinic keratosis · score 0.04
neoplasm · score 0.04
squamous cell carcinoma · score 0.04
oligodendroglioma · score 0.01
papillary thyroid carcinoma · score 0.01
breast ductal carcinoma in situ · score 0.01
Colon Sessile Serrated Adenoma/Polyp · score 0.01
visceral Leishmaniasis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60606-F1	alphafold	PREDICTED	70.38	—

Amino-acid sequence (82 residues)

MSATWTLSPE PLPPSTGPPV GAGLDAEQRT VFAFVLCLLV VLVLLMVRCV RILLDPYSRM PASSWTDHKE ALERGQFDYA LV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards