Myosin light polypeptide 6 (MYL6)

About Myosin light polypeptide 6

Myosin light polypeptide 6 (MYL6) is a protein from Homo sapiens identified by UniProt accession P60660, 151 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein name	Myosin light polypeptide 6
UniProt accession	P60660
Gene	MYL6
Organism	Homo sapiens
Length	151 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.29
breast adenocarcinoma · score 0.21
cutaneous melanoma · score 0.13
microscopic polyangiitis · score 0.07
non-alcoholic fatty liver disease · score 0.05
Inguinal hernia · score 0.03
fetal growth restriction · score 0.03
gonorrhea · score 0.03
melanoma · score 0.02
Obesity · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60660-F1	alphafold	PREDICTED	95.28	—

Amino-acid sequence (151 residues)

MCDFTEDQTA EFKEAFQLFD RTGDGKILYS QCGDVMRALG QNPTNAEVLK VLGNPKSDEM NVKVLDFEHF LPMLQTVAKN KDQGTYEDYV EGLRVFDKEG NGTVMGAEIR HVLVTLGEKM TEEEVEMLVA GHEDSNGCIN YEAFVRHILS G

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards