Small ribosomal subunit protein uS10 (RPS20)

About Small ribosomal subunit protein uS10

Small ribosomal subunit protein uS10 (RPS20) is a protein from Homo sapiens identified by UniProt accession P60866, 119 residues long. MolForge cross-references it against 0 known binders and 142 disease associations.

Target properties

Protein name	Small ribosomal subunit protein uS10
UniProt accession	P60866
Gene	RPS20
Organism	Homo sapiens
Length	119 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (142)

Diseases linked to this target (Open Targets).

Diamond-Blackfan anemia · score 0.52
Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
Blackfan-Diamond anemia · score 0.44
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
neurodegenerative disease · score 0.35
Becker muscular dystrophy · score 0.29
monocyte count · score 0.27

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60866-F1	alphafold	PREDICTED	85.23	—

Amino-acid sequence (119 residues)

MAFKDTGKTP VEPEVAIHRI RITLTSRNVK SLEKVCADLI RGAKEKNLKV KGPVRMPTKT LRITTRKTPC GEGSKTWDRF QMRIHKRLID LHSPSEIVKQ ITSISIEPGV EVEVTIADA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards