About Destrin
Destrin (DSTN) is a protein
from Homo sapiens identified by UniProt accession
P60981, 165 residues long.
MolForge cross-references it against 0 known binders and
163 disease associations.
Target properties
| Protein name | Destrin |
|---|
| UniProt accession | P60981 |
|---|
| Gene | DSTN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 165 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (163)
Diseases linked to this target (Open Targets).
- Alzheimer disease · score 0.32
- neurodegenerative disease · score 0.32
- Parkinson disease · score 0.32
- multiple sclerosis · score 0.32
- lysosomal storage disease · score 0.32
- neuroinflammatory disorder · score 0.30
- hematocrit · score 0.14
- Lisch epithelial corneal dystrophy · score 0.11
- high density lipoprotein cholesterol measurement · score 0.10
- body height · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P60981-F1 | alphafold | PREDICTED | 86.62 | — |
Amino-acid sequence (165 residues)
MASGVQVADE VCRIFYDMKV RKCSTPEEIK KRKKAVIFCL SADKKCIIVE EGKEILVGDV GVTITDPFKH FVGMLPEKDC RYALYDASFE TKESRKEELM FFLWAPELAP LKSKMIYASS KDAIKKKFQG IKHECQANGP EDLNRACIAE KLGGSLIVAF EGCPV
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