Keratinocyte differentiation-associated protein…

About Keratinocyte differentiation-associated protein

Keratinocyte differentiation-associated protein (KRTDAP) is a protein from Homo sapiens identified by UniProt accession P60985, 99 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Keratinocyte differentiation-associated protein
UniProt accession	P60985
Gene	KRTDAP
Organism	Homo sapiens
Length	99 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.03
breast cancer · score 0.01
non-small cell lung carcinoma · score 0.01
calf circumference measurement · score 0.01
dysplasia · score 0.01
oral squamous cell carcinoma · score 0.01
neoplasm · score 0.01
melanoma · score 0.01
cystic fibrosis · score 0.00
psoriasis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P60985-F1	alphafold	PREDICTED	58.82	—

Amino-acid sequence (99 residues)

MKIPVLPAVV LLSLLVLHSA QGATLGGPEE ESTIENYASR PEAFNTPFLN IDKLRSAFKA DEFLNWHALF ESIKRKLPFL NWDAFPKLKG LRSATPDAQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Keratinocyte differentiation-associated protein (KRTDAP)