Ras-related protein Rab-4B (RAB4B)

About Ras-related protein Rab-4B

Ras-related protein Rab-4B (RAB4B) is a protein from Homo sapiens identified by UniProt accession P61018, 213 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.

Target properties

Protein name	Ras-related protein Rab-4B
UniProt accession	P61018
Gene	RAB4B
Organism	Homo sapiens
Length	213 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61018-F1	alphafold	PREDICTED	88.45	—

Amino-acid sequence (213 residues)

MAETYDFLFK FLVIGSAGTG KSCLLHQFIE NKFKQDSNHT IGVEFGSRVV NVGGKTVKLQ IWDTAGQERF RSVTRSYYRG AAGALLVYDI TSRETYNSLA AWLTDARTLA SPNIVVILCG NKKDLDPERE VTFLEASRFA QENELMFLET SALTGENVEE AFLKCARTIL NKIDSGELDP ERMGSGIQYG DASLRQLRQP RSAQAVAPQP CGC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards