Cyclin-dependent kinases regulatory subunit 1 (CKS1B)

About Cyclin-dependent kinases regulatory subunit 1

Cyclin-dependent kinases regulatory subunit 1 (CKS1B) is a protein from Homo sapiens identified by UniProt accession P61024, 79 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.

Target properties

Protein name	Cyclin-dependent kinases regulatory subunit 1
UniProt accession	P61024
Gene	CKS1B
Organism	Homo sapiens
Length	79 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (95)

Diseases linked to this target (Open Targets).

breast neoplasm · score 0.42
head and neck squamous cell carcinoma · score 0.21
atrial fibrillation · score 0.16
breast adenocarcinoma · score 0.10
cancer · score 0.09
hepatocellular carcinoma · score 0.09
neoplasm · score 0.09
Miyoshi myopathy · score 0.09
acute myeloid leukemia · score 0.08
multiple myeloma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61024-F1	alphafold	PREDICTED	92.07	—

Amino-acid sequence (79 residues)

MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ SQGWVHYMIH EPEPHILLFR RPLPKKPKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards