About Ras-related protein Rab-10
Ras-related protein Rab-10 (RAB10) is a protein
from Homo sapiens identified by UniProt accession
P61026, 200 residues long.
MolForge cross-references it against 0 known binders and
105 disease associations.
Target properties
| Protein name | Ras-related protein Rab-10 |
|---|
| UniProt accession | P61026 |
|---|
| Gene | RAB10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 200 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (105)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- mean corpuscular volume · score 0.35
- mean corpuscular hemoglobin concentration · score 0.35
- mean corpuscular hemoglobin · score 0.31
- HbA1c measurement · score 0.24
- hemoglobin A1 measurement · score 0.22
- eosinophil count · score 0.18
- platelet component distribution width · score 0.16
- squamous cell lung carcinoma · score 0.12
- Red cell distribution width · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P61026-F1 | alphafold | PREDICTED | 85.73 | — |
Amino-acid sequence (200 residues)
MAKKTYDLLF KLLLIGDSGV GKTCVLFRFS DDAFNTTFIS TIGIDFKIKT VELQGKKIKL QIWDTAGQER FHTITTSYYR GAMGIMLVYD ITNGKSFENI SKWLRNIDEH ANEDVERMLL GNKCDMDDKR VVPKGKGEQI AREHGIRFFE TSAKANINIE KAFLTLAEDI LRKTPVKEPN SENVDISSGG GVTGWKSKCC
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