About Ras-related protein Rab-14
Ras-related protein Rab-14 (RAB14) is a protein
from Homo sapiens identified by UniProt accession
P61106, 215 residues long.
MolForge cross-references it against 0 known binders and
70 disease associations.
Target properties
| Protein name | Ras-related protein Rab-14 |
|---|
| UniProt accession | P61106 |
|---|
| Gene | RAB14 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 215 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (70)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- breast adenocarcinoma · score 0.25
- type 1 diabetes mellitus · score 0.14
- complication · score 0.14
- squamous cell lung carcinoma · score 0.12
- cytokine measurement · score 0.09
- response to vaccine · score 0.09
- breast cancer · score 0.08
- bladder transitional cell carcinoma · score 0.07
- hemoglobin measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P61106-F1 | alphafold | PREDICTED | 84.79 | — |
Amino-acid sequence (215 residues)
MATAPYNYSY IFKYIIIGDM GVGKSCLLHQ FTEKKFMADC PHTIGVEFGT RIIEVSGQKI KLQIWDTAGQ ERFRAVTRSY YRGAAGALMV YDITRRSTYN HLSSWLTDAR NLTNPNTVII LIGNKADLEA QRDVTYEEAK QFAEENGLLF LEASAKTGEN VEDAFLEAAK KIYQNIQDGS LDLNAAESGV QHKPSAPQGG RLTSEPQPQR EGCGC
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