Ras-related protein Rap-1b (RAP1B)

About Ras-related protein Rap-1b

Ras-related protein Rap-1b (RAP1B) is a protein from Homo sapiens identified by UniProt accession P61224, 184 residues long. MolForge cross-references it against 0 known binders and 201 disease associations.

Target properties

Protein name	Ras-related protein Rap-1b
UniProt accession	P61224
Gene	RAP1B
Organism	Homo sapiens
Length	184 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61224-F1	alphafold	PREDICTED	92.24	—

Amino-acid sequence (184 residues)

MREYKLVVLG SGGVGKSALT VQFVQGIFVE KYDPTIEDSY RKQVEVDAQQ CMLEILDTAG TEQFTAMRDL YMKNGQGFAL VYSITAQSTF NDLQDLREQI LRVKDTDDVP MILVGNKCDL EDERVVGKEQ GQNLARQWNN CAFLESSAKS KINVNEIFYD LVRQINRKTP VPGKARKKSS CQLL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards