Ras-related protein Rap-2b (RAP2B)

About Ras-related protein Rap-2b

Ras-related protein Rap-2b (RAP2B) is a protein from Homo sapiens identified by UniProt accession P61225, 183 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.

Target properties

Protein name	Ras-related protein Rap-2b
UniProt accession	P61225
Gene	RAP2B
Organism	Homo sapiens
Length	183 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61225-F1	alphafold	PREDICTED	90.63	—

Amino-acid sequence (183 residues)

MREYKVVVLG SGGVGKSALT VQFVTGSFIE KYDPTIEDFY RKEIEVDSSP SVLEILDTAG TEQFASMRDL YIKNGQGFIL VYSLVNQQSF QDIKPMRDQI IRVKRYERVP MILVGNKVDL EGEREVSYGE GKALAEEWSC PFMETSAKNK ASVDELFAEI VRQMNYAAQP NGDEGCCSAC VIL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards