About Protein max
Protein max (MAX) is a protein
from Homo sapiens identified by UniProt accession
P61244, 160 residues long.
MolForge cross-references it against 0 known binders and
295 disease associations.
Target properties
| Protein name | Protein max |
| UniProt accession | P61244 |
| Gene | MAX |
| Organism | Homo sapiens |
| Length | 160 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (295)
Diseases linked to this target (Open Targets).
- adrenal gland pheochromocytoma · score 0.81
- hereditary pheochromocytoma-paraganglioma · score 0.68
- Inherited cancer-predisposing syndrome · score 0.55
- hereditary neoplastic syndrome · score 0.55
- multiple myeloma · score 0.52
- neurodegenerative disease · score 0.51
- polydactyly-macrocephaly syndrome · score 0.47
- endometrial cancer · score 0.46
- colon adenocarcinoma · score 0.37
- pancreatic carcinoma · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P61244-F1 | alphafold | PREDICTED | 81.33 | — |
Amino-acid sequence (160 residues)
MSDNDDIEVE SDEEQPRFQS AADKRAHHNA LERKRRDHIK DSFHSLRDSV PSLQGEKASR AQILDKATEY IQYMRRKNHT HQQDIDDLKR QNALLEQQVR ALEKARSSAQ LQTNYPSSDN SLYTNAKGST ISAFDGGSDS SSESEPEEPQ SRKKLRMEAS
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