About Small ribosomal subunit protein eS1
Small ribosomal subunit protein eS1 (RPS3A) is a protein
from Homo sapiens identified by UniProt accession
P61247, 264 residues long.
MolForge cross-references it against 0 known binders and
57 disease associations.
Target properties
| Protein name | Small ribosomal subunit protein eS1 |
|---|
| UniProt accession | P61247 |
|---|
| Gene | RPS3A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 264 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (57)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- COVID-19 · score 0.37
- multiple myeloma · score 0.37
- severe acute respiratory syndrome · score 0.37
- Becker muscular dystrophy · score 0.29
- clear cell renal carcinoma · score 0.27
- qualitative or quantitative defects of dystrophin · score 0.26
- acute myeloid leukemia · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P61247-F1 | alphafold | PREDICTED | 82.91 | — |
Amino-acid sequence (264 residues)
MAVGKNKRLT KGGKKGAKKK VVDPFSKKDW YDVKAPAMFN IRNIGKTLVT RTQGTKIASD GLKGRVFEVS LADLQNDEVA FRKFKLITED VQGKNCLTNF HGMDLTRDKM CSMVKKWQTM IEAHVDVKTT DGYLLRLFCV GFTKKRNNQI RKTSYAQHQQ VRQIRKKMME IMTREVQTND LKEVVNKLIP DSIGKDIEKA CQSIYPLHDV FVRKVKMLKK PKFELGKLME LHGEGSSSGK ATGDETGAKV ERADGYEPPV QESV
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