About Large ribosomal subunit protein eL15
Large ribosomal subunit protein eL15 (RPL15) is a protein
from Homo sapiens identified by UniProt accession
P61313, 204 residues long.
MolForge cross-references it against 0 known binders and
85 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein eL15 |
|---|
| UniProt accession | P61313 |
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| Gene | RPL15 |
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| Organism | Homo sapiens |
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| Length | 204 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (85)
Diseases linked to this target (Open Targets).
- Blackfan-Diamond anemia · score 0.61
- Diamond-Blackfan anemia · score 0.56
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- Becker muscular dystrophy · score 0.29
- qualitative or quantitative defects of dystrophin · score 0.26
- intelligence · score 0.19
- cognitive function measurement · score 0.17
- glioblastoma multiforme · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P61313-F1 | alphafold | PREDICTED | 96.19 | — |
Amino-acid sequence (204 residues)
MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGVN QLKFARSLQS VAEERAGRHC GALRVLNSYW VGEDSTYKFF EVILIDPFHK AIRRNPDTQW ITKPVHKHRE MRGLTSAGRK SRGLGKGHKF HHTIGGSRRA AWRRRNTLQL HRYR
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