About Protein mago nashi homolog
Protein mago nashi homolog (MAGOH) is a protein
from Homo sapiens identified by UniProt accession
P61326, 146 residues long.
MolForge cross-references it against 0 known binders and
85 disease associations.
Target properties
| Protein name | Protein mago nashi homolog |
|---|
| UniProt accession | P61326 |
|---|
| Gene | MAGOH |
|---|
| Organism | Homo sapiens |
|---|
| Length | 146 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (85)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.38
- chronic lymphocytic leukemia · score 0.15
- blood metabolite measurement · score 0.12
- emotional symptom measurement · score 0.12
- serum metabolite measurement · score 0.10
- brain measurement · score 0.09
- cortical thickness · score 0.08
- cortical surface area measurement · score 0.08
- self reported educational attainment · score 0.08
- acylcarnitine measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P61326-F1 | alphafold | PREDICTED | 93.74 | — |
Amino-acid sequence (146 residues)
MESDFYLRYY VGHKGKFGHE FLEFEFRPDG KLRYANNSNY KNDVMIRKEA YVHKSVMEEL KRIIDDSEIT KEDDALWPPP DRVGRQELEI VIGDEHISFT TSKIGSLIDV NQSKDPEGLR VFYYLVQDLK CLVFSLIGLH FKIKPI
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