Osteocrin (OSTN)

Homo sapiens — UniProt P61366

Gene: OSTNHomo sapiensSwissProt reviewed

About Osteocrin

Osteocrin (OSTN) is a protein from Homo sapiens identified by UniProt accession P61366, 133 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.

Target properties

Protein nameOsteocrin
UniProt accessionP61366
GeneOSTN
OrganismHomo sapiens
Length133 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (64)

Diseases linked to this target (Open Targets).

  • body height · score 0.44
  • injury · score 0.26
  • sarcopenia · score 0.08
  • Obesity · score 0.07
  • atrial fibrillation · score 0.06
  • cancer · score 0.05
  • myocardial infarction · score 0.05
  • insulin resistance · score 0.05
  • type 2 diabetes mellitus · score 0.04
  • metabolic disease · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P61366-F1alphafoldPREDICTED65.61—

Amino-acid sequence (133 residues)

MLDWRLASAH FILAVTLTLW SSGKVLSVDV TTTEAFDSGV IDVQSTPTVR EEKSATDLTA KLLLLDELVS LENDVIETKK KRSFSGFGSP LDRLSAGSVD HKGKQRKVVD HPKRRFGIPM DRIGRNRLSN SRG

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Quick facts

UniProtP61366
GeneOSTN
OrganismHomo sapiens
Length133
Binders0
Diseases64
View on UniProt