Large ribosomal subunit protein eL43 (RPL37A)

About Large ribosomal subunit protein eL43

Large ribosomal subunit protein eL43 (RPL37A) is a protein from Homo sapiens identified by UniProt accession P61513, 92 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL43
UniProt accession	P61513
Gene	RPL37A
Organism	Homo sapiens
Length	92 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
cortical thickness · score 0.32
cortical surface area measurement · score 0.32
neurodegenerative disease · score 0.31
brain measurement · score 0.31
vital capacity · score 0.31
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61513-F1	alphafold	PREDICTED	96.33	—

Amino-acid sequence (92 residues)

MAKRTKKVGI VGKYGTRYGA SLRKMVKKIE ISQHAKYTCS FCGKTKMKRR AVGIWHCGSC MKTVAGGAWT YNTTSAVTVK SAIRRLKELK DQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards