Transforming protein RhoA (RHOA)

About Transforming protein RhoA

Transforming protein RhoA (RHOA) is a protein from Homo sapiens identified by UniProt accession P61586, 193 residues long. MolForge cross-references it against 0 known binders and 786 disease associations.

Target properties

Protein name	Transforming protein RhoA
UniProt accession	P61586
Gene	RHOA
Organism	Homo sapiens
Length	193 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61586-F1	alphafold	PREDICTED	93.58	—

Amino-acid sequence (193 residues)

MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD LRNDEHTRRE LAKMKQEPVK PEEGRDMANR IGAFGYMECS AKTKDGVREV FEMATRAALQ ARRGKKKSGC LVL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards