About N-alpha-acetyltransferase 20
N-alpha-acetyltransferase 20 (NAA20) is a protein
from Homo sapiens identified by UniProt accession
P61599, 178 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | N-alpha-acetyltransferase 20 |
|---|
| UniProt accession | P61599 |
|---|
| Gene | NAA20 |
|---|
| Organism | Homo sapiens |
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| Length | 178 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.38
- autosomal recessive non-syndromic intellectual disability · score 0.37
- platelet component distribution width · score 0.09
- mean platelet volume · score 0.08
- hepatocellular carcinoma · score 0.08
- appendicular lean mass · score 0.08
- serum albumin measurement · score 0.07
- body height · score 0.03
- neoplasm · score 0.02
- triple-negative breast cancer · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P61599-F1 | alphafold | PREDICTED | 94.01 | — |
Amino-acid sequence (178 residues)
MTTLRAFTCD DLFRFNNINL DPLTETYGIP FYLQYLAHWP EYFIVAEAPG GELMGYIMGK AEGSVAREEW HGHVTALSVA PEFRRLGLAA KLMELLEEIS ERKGGFFVDL FVRVSNQVAV NMYKQLGYSV YRTVIEYYSA SNGEPDEDAY DMRKALSRDT EKKSIIPLPH PVRPEDIE
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