Neurocalcin-delta (NCALD)

Homo sapiens — UniProt P61601

Gene: NCALDHomo sapiensSwissProt reviewed

About Neurocalcin-delta

Neurocalcin-delta (NCALD) is a protein from Homo sapiens identified by UniProt accession P61601, 193 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.

Target properties

Protein nameNeurocalcin-delta
UniProt accessionP61601
GeneNCALD
OrganismHomo sapiens
Length193 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (96)

Diseases linked to this target (Open Targets).

  • Red cell distribution width · score 0.47
  • FEV/FVC ratio · score 0.45
  • Beta blocking agent use measurement · score 0.33
  • coronary artery disease · score 0.32
  • hypertension · score 0.32
  • hemoglobin A1 measurement · score 0.32
  • peak expiratory flow · score 0.32
  • forced expiratory volume · score 0.32
  • neurodegenerative disease · score 0.30
  • cardiovascular disease · score 0.29

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P61601-F1alphafoldPREDICTED86.32—

Amino-acid sequence (193 residues)

MGKQNSKLRP EVMQDLLEST DFTEHEIQEW YKGFLRDCPS GHLSMEEFKK IYGNFFPYGD ASKFAEHVFR TFDANGDGTI DFREFIIALS VTSRGKLEQK LKWAFSMYDL DGNGYISKAE MLEIVQAIYK MVSSVMKMPE DESTPEKRTE KIFRQMDTNR DGKLSLEEFI RGAKSDPSIV RLLQCDPSSA GQF

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Quick facts

UniProtP61601
GeneNCALD
OrganismHomo sapiens
Length193
Binders0
Diseases96
View on UniProt