10 kDa heat shock protein, mitochondrial (HSPE1)

About 10 kDa heat shock protein, mitochondrial

10 kDa heat shock protein, mitochondrial (HSPE1) is a protein from Homo sapiens identified by UniProt accession P61604, 102 residues long. MolForge cross-references it against 0 known binders and 192 disease associations.

Target properties

Protein name	10 kDa heat shock protein, mitochondrial
UniProt accession	P61604
Gene	HSPE1
Organism	Homo sapiens
Length	102 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (192)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
schizophrenia · score 0.25
body height · score 0.21
cortical thickness · score 0.21
brain measurement · score 0.20
cortical surface area measurement · score 0.20
autism spectrum disorder · score 0.16
allergic rhinitis · score 0.15
Eczematoid dermatitis · score 0.15
neuroimaging measurement · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61604-F1	alphafold	PREDICTED	87.63	—

Amino-acid sequence (102 residues)

MAGQAFRKFL PLFDRVLVER SAAETVTKGG IMLPEKSQGK VLQATVVAVG SGSKGKGGEI QPVSVKVGDK VLLPEYGGTK VVLDDKDYFL FRDGDILGKY VD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards